ec cell造句

• By aggregating the cells into embryonic body, EC cells can also process differentiation.
• Tissue beneath EC cells typically contains abundant fenestrated capillaries, lymph vessels and small unmyelinated nerve fibres.
• Ongoing research indicates abnormal EC cell populations and therefore 5-HT signalling may significantly contribute to gastrointestinal dysfunction.
• Most EC cells communicate with the lumen of intestinal crypts through apical microvilli protrusions and are referred to as  open.
• A proportion of EC cells also present do not protrude into the crypt lumen and are subsequently referred to as  closed.
• EC cells typically extend down to the basal lamina with cytoplasmic extensions known to pass through the connective tissue and neighbouring glands.
• Layer V EC cells have strong recurrent excitatory synapses much like CA3 layers in the hippocampus and when provoked are capable of burst activity.
• Release of the vesicles occurs after chemical, neurological or mechanical stimulation of the EC cells and is predominantly calcium dependent, suggesting excretion via exocytosis.
• Likewise reduced populations of EC cells in patients suffering chronic constipation has been observed, indicating a lack of 5-HT and therefore decrease GI motility and secretion.
• The serotonin synthesised by EC cells is predominately exocytosed from the basal border, but is also known to be apically secreted into the lumen of the gut and can be present in faecal samples.